SECURITIES (DISCLOSURE OF INTERESTS) DAILY SUMMARIES - (GEM)                         PRINTED: 27/09/02  PAGE:   1
                                                        DIRECTORS'/CHIEF EXECUTIVES' NOTIFICATIONS REPORT - B
                                                            (GRANTS, ASSIGNMENTS AND EXERCISES OF RIGHTS)

 STOCK NAME : Essex Bio-Tech                 (08151)

       Director/Chief Executive        G/E     Class                 Company Name                 Quantity       Exercise Period   Ex. Price  Consideration       Note
 ------------------------------------  --- ---------------  -------------------------------  ------------------  ---------------  ---------- ---------------  -----------
 NGIAM MIA JE PATRICK                   G  OPT              ESSEX BIO-TECHNOLOGY LIMITED            4,500,000                         0.100                1             

                                        E  OPT              ESSEX BIO-TECHNOLOGY LIMITED            2,250,000           -              -                   0             

 ZHONG SHENG                            G  OPT              ESSEX BIO-TECHNOLOGY LIMITED            3,000,000                         0.100                1             

                                        E  OPT              ESSEX BIO-TECHNOLOGY LIMITED            1,500,000           -              -                   0             

 FANG HAIZHOU                           G  OPT              ESSEX BIO-TECHNOLOGY LIMITED            4,000,000                         0.100                1             

                                        E  OPT              ESSEX BIO-TECHNOLOGY LIMITED            2,000,000           -              -                   0             

                                                                     *****  END OF REPORT  *****

NOTE


N1      Exercise of share options